
Domenico Aprile, PhD
Assistant Professor
Professional Information
Biography
Dr. Aprile is a molecular biologist and Assistant Professor (RTD-A) at the University of Campania "Luigi Vanvitelli," where he teaches Molecular Biology in the single-cycle Master's Degree in Medicine and Surgery and in the PhD program in Public Health. His research focuses on cellular senescence, stem cell biology, and the molecular mechanisms involved in neurodegeneration and aging. He is currently involved in the MNESYS project (PE0000006, PNRR), exploring multiscale approaches to the study of the nervous system in health and disease. His work includes the use of Muse cells, senolytic compounds, and experimental models exposed to low-dose radiation. He has gained international research experience through fellowships in Japan (JSPS), the Netherlands (ERIBA), and Portugal (IMM Lisboa). In parallel, he co-founded AMRITA Nutraceutics, a startup dedicated to the development of innovative compounds targeting senescence and protecting against radiation-induced damage. He is also actively engaged in the scientific community, having served as a member of the organizing committee for several national and international conferences, including the Stem Cell Research Italy and SIBBM meetings.
Specialization
Stem Cell Biology
Education
PhD in Clinical and Experimental Medical Sciences (2018-2022); University of Campania "Luigi Vanvitelli", Naples, Italy; *Thesis: Role of SSEA-3 in MUSE cell stemness and lineage commitment*; *Honors: Cum Laude + Doctor Europaeus*; MSc in Biological Sciences (Molecular Diagnostics) (2016-2018); University of Naples "Federico II", Italy — 110/110 cum laude; BSc in Biological Sciences (2012-2015); University of Naples "Federico II", Italy — 110/110 cum laude
Research & Publications
Dr. Aprile's research concentrates on cellular senescence mechanisms, stem cell biology (particularly Muse cells), and molecular pathways involved in neurodegeneration and aging. His work explores the senescence-associated secretory phenotype (SASP), the role of growth factors in cellular aging, and the development of potential senotherapeutics.